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Royal Society of Chemistry

Article Metrics

Top-down fabrication meets bottom-up synthesis for nanoelectronic barcoding of microparticles

Overview of attention for article published in Lab on a Chip - Miniaturisation for Chemistry & Biology, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 3,654)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
20 news outlets
blogs
2 blogs
twitter
4 tweeters
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
30 Mendeley
Title
Top-down fabrication meets bottom-up synthesis for nanoelectronic barcoding of microparticles
Published in
Lab on a Chip - Miniaturisation for Chemistry & Biology, January 2017
DOI 10.1039/c7lc00035a
Pubmed ID
Authors

Pengfei Xie, Xinnan Cao, Zhongtian Lin, Mehdi Javanmard

Abstract

Traditional optical and plasmonic techniques for barcoding of micro-particles for multiplexed bioassays are generally high in throughput, however bulky instrumentation is often required for performing readout. Electrical impedance based detection allows for ultra-compact instrumentation footprint necessary for wearable devices, however to date, the lack of ability to electronically barcode micro-particles has been a long standing bottleneck towards enabling multiplexed electronic biomarker assays. Nanoelectronic barcoding, which to the best of our knowledge is the first impedance based solution for micro-particle barcoding, works by forming tunable nano-capacitors on the surface of micro-spheres, effectively modulating the frequency dependent dielectric properties of the spheres allowing one bead barcode to be distinguished from another. Nanoelectronic barcoding uses a well-known, but unexplored electromagnetic phenomenon of micro-particles: the Clausius-Mossotti (CM) factor spectrum of a Janus particle (JP) shifts depending on the zeta (wall) potential of the metallic half of the microsphere, and the fact that the complex impedance spectrum of a particle directly corresponds to the CM factor spectrum. A one-to-one correspondence will be established between each biomarker and the corresponding engineered microsphere. This transformative new method for barcoding will enable a new class of handheld and wearable biosensors capable of multiplexed continuous temporal bio-monitoring. The proposed nano-electronically barcoded particles utilize both bottom-up synthesis and top-down fabrication to enable precisely engineered frequency dependent dielectric signatures. Multi-frequency lock-in measurements of the complex impedance, in conjunction with multi-variate analysis of impedance data, allows for particle differentiation using a fully functional ultra-compact electronic detector.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 37%
Student > Master 6 20%
Researcher 5 17%
Professor 2 7%
Student > Bachelor 1 3%
Other 1 3%
Unknown 4 13%
Readers by discipline Count As %
Engineering 14 47%
Biochemistry, Genetics and Molecular Biology 3 10%
Agricultural and Biological Sciences 2 7%
Materials Science 2 7%
Physics and Astronomy 1 3%
Other 3 10%
Unknown 5 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 162. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2017.
All research outputs
#64,353
of 11,454,620 outputs
Outputs from Lab on a Chip - Miniaturisation for Chemistry & Biology
#4
of 3,654 outputs
Outputs of similar age
#3,867
of 267,707 outputs
Outputs of similar age from Lab on a Chip - Miniaturisation for Chemistry & Biology
#1
of 60 outputs
Altmetric has tracked 11,454,620 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,654 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,707 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.